Research onlyFor laboratory research · Not intended for human or animal application
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CagriSema

Two satiety routes pre-mixed: amylin alongside GLP-1.

4.7 · 15 reviews
33% offResearch only
CagriSema, research-grade peptide vial
€ 69,95€ 104,95

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Bacteriostatic water

Needed to reconstitute lyophilised vials.

Insulin needles

Alcohol swabs

Quantity

1
Bulk discountup to −26%

1 more for −10% off

Shipping €7.95 · free from €125

In stock
Ships from NL · 1–2 day EU delivery
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Under the name CagriSema, Novo Nordisk studies two metabolic peptides as one whole: cagrilintide, an amylin analogue, and semaglutide, a GLP-1 agonist. We supply that pairing pre-mixed in one lyophilised vial. The Phase 3 REDEFINE programme mapped the combination, but as of June 2026 it is approved as a medicine nowhere. What you buy here is therefore not a medicine but a research-grade peptide, at ≥99% HPLC purity per component, dispatched the same working day from the Netherlands.

Which two substances are in here?

CagriSema is the name Novo Nordisk uses for the research combination of cagrilintide and semaglutide. The first is an amylin analogue, the second a GLP-1 agonist and also the substance that became clinically known as Ozempic and Wegovy. The research is aimed mainly at obesity and type 2 diabetes. The thinking behind it is simple: two different satiety routes that complement each other.

Two hormones, two routes

The two components each act on a different hormone. Semaglutide mimics the gut hormone GLP-1, which is tied to a feeling of fullness and slower gastric emptying. Cagrilintide mimics amylin, a second satiety route that GLP-1 substances do nothing with. The two together are thought to give a stronger metabolic response in research than either on its own. What is known about this comes from the clinical studies of Novo Nordisk.

REDEFINE and where approval stands

The Phase 3 REDEFINE programme mapped the combination. Substantial weight loss was seen, though the figures came in below what had been hoped for beforehand, and it was precisely that nuance that drew a lot of press attention. As of June 2026 the combination is approved as a medicine nowhere: an application is pending with the US FDA, and a European decision is still awaited. Through the pharmacy, then, it is not to be had. What is known sits in the studies and the medical literature.

Placed next to Wegovy, Ozempic and tirzepatide

The comparison with the well-known weight-loss medicines comes up often, and the difference lies in the number of routes. Wegovy and Ozempic contain only semaglutide and so stay with GLP-1. CagriSema lays the amylin route beside it with cagrilintide. Tirzepatide, sold as Mounjaro and Zepbound, goes about it differently again: one molecule that activates both GLP-1 and GIP. In head-to-head research CagriSema fell just short of tirzepatide, which was widely discussed at the time. One difference weighs more: semaglutide and tirzepatide are approved medicines, this combination is not yet. The individual building blocks sit separately in the range.

Why we supply it pre-mixed

In the research the two are studied as one combination, not as two separate injections. That is why they sit pre-mixed in one lyophilised vial with us: the ratio between the components is fixed and you need weigh nothing out in your protocol. That saves handling steps and keeps run-to-run variation small. If you would rather titrate separately, order the components individually and make up each peptide on its own.

What the clinical research describes

The side effects described most often in clinical research sit in the gastrointestinal area: nausea, vomiting and constipation, mainly in the first weeks and when the dose is raised. The profile therefore resembles that of other GLP-1-based substances. Those are observations in humans under medical supervision and so say nothing about laboratory use.

Making it up, storing and a double check

You receive lyophilised powder in one vial in which both peptides have already been brought together. In research that is made up with bacteriostatic water; we give no dosing or administration advice. Keep the unopened vial dry, dark and cool; once the solution is made, it goes into the fridge at 2–8 °C, protected from light, or into the freezer for longer storage. Every batch goes through purity (≥99% by HPLC) and identity for both components. The exact composition is in the table at the bottom of this page.

Frequently asked questions

What buyers write after delivery.

Verified buyers in the Netherlands, Belgium and Germany

★★★★★4.9 / 5Verified
★★★★★

Ordered Friday 3 PM, delivered Tuesday morning in Utrecht. Neatly packed and the COA simply arrived by email.

Sven K.

Verified purchase

BPC-157
★★★★★

Finally a supplier that just shows the HPLC + MS figures. Purity was exactly as promised.

Lotte v.d. B.

Verified purchase

TB-500
★★★★★

Fast parcel out of the Netherlands. Emailed a question, got a reply within a few hours. Top service.

Paul M.

Verified purchase

GHK-Cu
★★★★★

Next business day in Rotterdam. Sturdily packed, vial arrived intact. Will definitely order again.

Marco R.

Verified purchase

BPC-157
★★★★★

Ordered around 3 PM, delivered Wednesday morning. The lot number on the vial matched the report I asked for.

Niels J.

Verified purchase

Ipamorelin
★★★★★

Within 24 hours from NL stock. COA with MS identity confirmation — hard to find anywhere else.

Jonas W.

Verified purchase

CJC-1295
★★★★

Delivery spot-on, COA detailed. Would appreciate a more extensive FAQ per peptide on the site.

Eva R.

Verified purchase

GHK-Cu
★★★★★

Ordered Tuesday before 4 PM, at my door Wednesday in Breda. Confirmation and dispatch email arrived neatly in sequence.

Bram H.

Verified purchase

Semaglutide
★★★★★

Genuinely from NL stock, so here within a day. Vial well freeze-dried, everything tightly packed.

Femke S.

Verified purchase

Retatrutide
★★★★

Purity on the HPLC comfortably above 99%. Delivery a day later than hoped, nothing else to fault.

Thijs M.

Verified purchase

TB-500
★★★★★

Ordered Friday 3 PM, delivered Tuesday morning in Utrecht. Neatly packed and the COA simply arrived by email.

Sven K.

Verified purchase

BPC-157
★★★★★

Finally a supplier that just shows the HPLC + MS figures. Purity was exactly as promised.

Lotte v.d. B.

Verified purchase

TB-500
★★★★★

Fast parcel out of the Netherlands. Emailed a question, got a reply within a few hours. Top service.

Paul M.

Verified purchase

GHK-Cu
★★★★★

Next business day in Rotterdam. Sturdily packed, vial arrived intact. Will definitely order again.

Marco R.

Verified purchase

BPC-157
★★★★★

Ordered around 3 PM, delivered Wednesday morning. The lot number on the vial matched the report I asked for.

Niels J.

Verified purchase

Ipamorelin
★★★★★

Within 24 hours from NL stock. COA with MS identity confirmation — hard to find anywhere else.

Jonas W.

Verified purchase

CJC-1295
★★★★

Delivery spot-on, COA detailed. Would appreciate a more extensive FAQ per peptide on the site.

Eva R.

Verified purchase

GHK-Cu
★★★★★

Ordered Tuesday before 4 PM, at my door Wednesday in Breda. Confirmation and dispatch email arrived neatly in sequence.

Bram H.

Verified purchase

Semaglutide
★★★★★

Genuinely from NL stock, so here within a day. Vial well freeze-dried, everything tightly packed.

Femke S.

Verified purchase

Retatrutide
★★★★

Purity on the HPLC comfortably above 99%. Delivery a day later than hoped, nothing else to fault.

Thijs M.

Verified purchase

TB-500
★★★★★

The BPC + TB stack comes as two separate vials, each with its own COA. Not pre-mixed — exactly what I wanted.

Tom B.

Verified purchase

Recovery Stack
★★★★★

The COA was clear and readable. Delivered the next business day in The Hague. Helpful support by email.

Charlotte F.

Verified purchase

Selank
★★★★★

Emailed a question about storage temperature and got a concrete answer instead of a stock phrase. Saved me the digging.

Anouk d. V.

Verified purchase

Semax
★★★★★

Purity per COA 99.3%. Vial nicely freeze-dried, no yellow discolouration. Shipping from NL trouble-free.

Lukas K.

Verified purchase

Epitalon
★★★★★

Emailed a question on Saturday, Monday morning I got a reply from a real person. No cookie-cutter template. Real service.

Sara P.

Verified purchase

BPC-157
★★★★★

Shipped to Tilburg in one business day. Identity neatly confirmed by MS on the analysis report.

Daniel S.

Verified purchase

TB-500
★★★★★

Second order. The first was problem-free, so no reason to look elsewhere. COA again with HPLC + MS figures.

Iris K.

Verified purchase

Ipamorelin
★★★★★

Messaged a question about storage, got a clear answer. Nice that there is simply someone reachable.

Joris V.

Verified purchase

CJC-1295
★★★★★

Purity on the report matched what the page said. Delivered next day in Nijmegen. Exactly what I was after.

Sanne D.

Verified purchase

Tirzepatide
★★★★★

Shipped quickly from the Netherlands, and the COA confirmed the purity nicely. Third time ordering here without complaints.

Ruben T.

Verified purchase

GHK-Cu
★★★★★

The BPC + TB stack comes as two separate vials, each with its own COA. Not pre-mixed — exactly what I wanted.

Tom B.

Verified purchase

Recovery Stack
★★★★★

The COA was clear and readable. Delivered the next business day in The Hague. Helpful support by email.

Charlotte F.

Verified purchase

Selank
★★★★★

Emailed a question about storage temperature and got a concrete answer instead of a stock phrase. Saved me the digging.

Anouk d. V.

Verified purchase

Semax
★★★★★

Purity per COA 99.3%. Vial nicely freeze-dried, no yellow discolouration. Shipping from NL trouble-free.

Lukas K.

Verified purchase

Epitalon
★★★★★

Emailed a question on Saturday, Monday morning I got a reply from a real person. No cookie-cutter template. Real service.

Sara P.

Verified purchase

BPC-157
★★★★★

Shipped to Tilburg in one business day. Identity neatly confirmed by MS on the analysis report.

Daniel S.

Verified purchase

TB-500
★★★★★

Second order. The first was problem-free, so no reason to look elsewhere. COA again with HPLC + MS figures.

Iris K.

Verified purchase

Ipamorelin
★★★★★

Messaged a question about storage, got a clear answer. Nice that there is simply someone reachable.

Joris V.

Verified purchase

CJC-1295
★★★★★

Purity on the report matched what the page said. Delivered next day in Nijmegen. Exactly what I was after.

Sanne D.

Verified purchase

Tirzepatide
★★★★★

Shipped quickly from the Netherlands, and the COA confirmed the purity nicely. Third time ordering here without complaints.

Ruben T.

Verified purchase

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