Research onlyFor laboratory research · Not intended for human or animal application
BasePurity

Gonadorelin

GnRH of ten amino acids, the opening signal of the hormone chain.

4.4 · 19 reviews
99.2% HPLCLab-verifiedResearch only
Gonadorelin, research-grade peptide vial
€ 24,95

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Bacteriostatic water

Needed to reconstitute lyophilised vials.

Insulin needles

Alcohol swabs

Quantity

1
Bulk discountup to −26%

1 more for −10% off

Shipping €7.95 · free from €125

In stock
Ships from NL · 1–2 day EU delivery
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Gonadorelin is the synthetic form of GnRH, the ten-amino-acid hormone with which the hypothalamus prompts the pituitary to release LH and FSH. That places it right at the start of the hormone chain steering the gonads, and it is precisely that position which makes it interesting in research. We supply it as a research-grade vial at ≥99% HPLC purity, dispatched the same working day from the Netherlands.

What gonadorelin research turns on

Gonadorelin is the synthetic form of GnRH (gonadotropin-releasing hormone), the hormone with which the hypothalamus drives the pituitary. In short: gonadorelin signals the pituitary to release two other hormones, LH (luteinizing hormone) and FSH (follicle-stimulating hormone). Those two in turn drive the gonads. In research, gonadorelin is therefore used to study the pituitary-gonadal axis. It was also used as a medicine in fertility research and diagnostics, but those branded products (Factrel, LutrePulse) are largely off the market.

The pulsing signal from the hypothalamus

What is special about gonadorelin lies in the rhythm. The pituitary responds to pulses of GnRH, not to a constant stream. When gonadorelin is given in short pulses in research, it stimulates the release of LH and FSH, it mimics the natural rhythm of the hypothalamus. When it is given continuously, the opposite happens: the receptors become insensitive and LH/FSH release falls. That dual behaviour, stimulating in pulses, suppressing when continuous, is exactly why gonadorelin is of interest in research. What we know about this comes from the clinical and scientific literature.

Placed next to hCG

Gonadorelin and hCG are often compared because both relate to the sex-hormone axis, but they act at a very different point. Gonadorelin works at the top of the chain: it prompts the pituitary to make LH and FSH itself. hCG skips that step, it mimics LH and acts directly on the gonads, bypassing the pituitary. In the research and TRT context, gonadorelin is therefore seen as the substance that keeps the natural axis switched on, while hCG mimics the axis from below. BasePurity does not sell hCG; this comparison is here purely for information.

The axis underneath TRT research

In the context of testosterone replacement (TRT), gonadorelin is a much-discussed topic. The idea behind it: during an external testosterone course, the body-own LH/FSH production stalls, which makes the gonads less active. It is thought that pulsatile GnRH stimulation may keep that axis switched on in research. What is known about this is described in the scientific literature.

What is reported about tolerability?

In the clinical literature, gonadorelin is generally well tolerated. The described side effects are mostly mild: headache, nausea and an irritated or painful injection site; sometimes hot flushes. These are observations from medical use under supervision, not data that says anything about laboratory use. BasePurity supplies gonadorelin solely as a research substance and gives no dosing or safety advice for personal use. For the full side effects we refer to the medical literature and a doctor or pharmacist.

Making it up and storing it

Gonadorelin is supplied as a lyophilised powder in a vial. For research it is mixed with bacteriostatic water; BasePurity gives no dosing or administration advice. Store the unopened vial dry, dark and cool. Gonadorelin in solution is less stable than many other peptides: after mixing it goes in the fridge (2–8 °C), protected from light, and is used within a short time; for longer storage the unopened vial can go in the freezer. The specifications in the table at the bottom of this page are intended for your research documentation.

What we check per batch

Every batch of gonadorelin is checked in the lab for purity (≥99% HPLC) and identity. Precisely for a substance whose branded medicine is off the market, that testing is what sets it apart from anonymous suppliers: you know exactly what you are holding. Per lot we record the purity and identity data. The exact specifications, sequence, molecular weight and purity, are in the table at the bottom of this page.

Frequently asked questions

What buyers write after delivery.

Verified buyers in the Netherlands, Belgium and Germany

★★★★★4.9 / 5Verified
★★★★★

Ordered Friday 3 PM, delivered Tuesday morning in Utrecht. Neatly packed and the COA simply arrived by email.

Sven K.

Verified purchase

BPC-157
★★★★★

Finally a supplier that just shows the HPLC + MS figures. Purity was exactly as promised.

Lotte v.d. B.

Verified purchase

TB-500
★★★★★

Fast parcel out of the Netherlands. Emailed a question, got a reply within a few hours. Top service.

Paul M.

Verified purchase

GHK-Cu
★★★★★

Next business day in Rotterdam. Sturdily packed, vial arrived intact. Will definitely order again.

Marco R.

Verified purchase

BPC-157
★★★★★

Ordered around 3 PM, delivered Wednesday morning. The lot number on the vial matched the report I asked for.

Niels J.

Verified purchase

Ipamorelin
★★★★★

Within 24 hours from NL stock. COA with MS identity confirmation — hard to find anywhere else.

Jonas W.

Verified purchase

CJC-1295
★★★★

Delivery spot-on, COA detailed. Would appreciate a more extensive FAQ per peptide on the site.

Eva R.

Verified purchase

GHK-Cu
★★★★★

Ordered Tuesday before 4 PM, at my door Wednesday in Breda. Confirmation and dispatch email arrived neatly in sequence.

Bram H.

Verified purchase

Semaglutide
★★★★★

Genuinely from NL stock, so here within a day. Vial well freeze-dried, everything tightly packed.

Femke S.

Verified purchase

Retatrutide
★★★★

Purity on the HPLC comfortably above 99%. Delivery a day later than hoped, nothing else to fault.

Thijs M.

Verified purchase

TB-500
★★★★★

Ordered Friday 3 PM, delivered Tuesday morning in Utrecht. Neatly packed and the COA simply arrived by email.

Sven K.

Verified purchase

BPC-157
★★★★★

Finally a supplier that just shows the HPLC + MS figures. Purity was exactly as promised.

Lotte v.d. B.

Verified purchase

TB-500
★★★★★

Fast parcel out of the Netherlands. Emailed a question, got a reply within a few hours. Top service.

Paul M.

Verified purchase

GHK-Cu
★★★★★

Next business day in Rotterdam. Sturdily packed, vial arrived intact. Will definitely order again.

Marco R.

Verified purchase

BPC-157
★★★★★

Ordered around 3 PM, delivered Wednesday morning. The lot number on the vial matched the report I asked for.

Niels J.

Verified purchase

Ipamorelin
★★★★★

Within 24 hours from NL stock. COA with MS identity confirmation — hard to find anywhere else.

Jonas W.

Verified purchase

CJC-1295
★★★★

Delivery spot-on, COA detailed. Would appreciate a more extensive FAQ per peptide on the site.

Eva R.

Verified purchase

GHK-Cu
★★★★★

Ordered Tuesday before 4 PM, at my door Wednesday in Breda. Confirmation and dispatch email arrived neatly in sequence.

Bram H.

Verified purchase

Semaglutide
★★★★★

Genuinely from NL stock, so here within a day. Vial well freeze-dried, everything tightly packed.

Femke S.

Verified purchase

Retatrutide
★★★★

Purity on the HPLC comfortably above 99%. Delivery a day later than hoped, nothing else to fault.

Thijs M.

Verified purchase

TB-500
★★★★★

The BPC + TB stack comes as two separate vials, each with its own COA. Not pre-mixed — exactly what I wanted.

Tom B.

Verified purchase

Recovery Stack
★★★★★

The COA was clear and readable. Delivered the next business day in The Hague. Helpful support by email.

Charlotte F.

Verified purchase

Selank
★★★★★

Emailed a question about storage temperature and got a concrete answer instead of a stock phrase. Saved me the digging.

Anouk d. V.

Verified purchase

Semax
★★★★★

Purity per COA 99.3%. Vial nicely freeze-dried, no yellow discolouration. Shipping from NL trouble-free.

Lukas K.

Verified purchase

Epitalon
★★★★★

Emailed a question on Saturday, Monday morning I got a reply from a real person. No cookie-cutter template. Real service.

Sara P.

Verified purchase

BPC-157
★★★★★

Shipped to Tilburg in one business day. Identity neatly confirmed by MS on the analysis report.

Daniel S.

Verified purchase

TB-500
★★★★★

Second order. The first was problem-free, so no reason to look elsewhere. COA again with HPLC + MS figures.

Iris K.

Verified purchase

Ipamorelin
★★★★★

Messaged a question about storage, got a clear answer. Nice that there is simply someone reachable.

Joris V.

Verified purchase

CJC-1295
★★★★★

Purity on the report matched what the page said. Delivered next day in Nijmegen. Exactly what I was after.

Sanne D.

Verified purchase

Tirzepatide
★★★★★

Shipped quickly from the Netherlands, and the COA confirmed the purity nicely. Third time ordering here without complaints.

Ruben T.

Verified purchase

GHK-Cu
★★★★★

The BPC + TB stack comes as two separate vials, each with its own COA. Not pre-mixed — exactly what I wanted.

Tom B.

Verified purchase

Recovery Stack
★★★★★

The COA was clear and readable. Delivered the next business day in The Hague. Helpful support by email.

Charlotte F.

Verified purchase

Selank
★★★★★

Emailed a question about storage temperature and got a concrete answer instead of a stock phrase. Saved me the digging.

Anouk d. V.

Verified purchase

Semax
★★★★★

Purity per COA 99.3%. Vial nicely freeze-dried, no yellow discolouration. Shipping from NL trouble-free.

Lukas K.

Verified purchase

Epitalon
★★★★★

Emailed a question on Saturday, Monday morning I got a reply from a real person. No cookie-cutter template. Real service.

Sara P.

Verified purchase

BPC-157
★★★★★

Shipped to Tilburg in one business day. Identity neatly confirmed by MS on the analysis report.

Daniel S.

Verified purchase

TB-500
★★★★★

Second order. The first was problem-free, so no reason to look elsewhere. COA again with HPLC + MS figures.

Iris K.

Verified purchase

Ipamorelin
★★★★★

Messaged a question about storage, got a clear answer. Nice that there is simply someone reachable.

Joris V.

Verified purchase

CJC-1295
★★★★★

Purity on the report matched what the page said. Delivered next day in Nijmegen. Exactly what I was after.

Sanne D.

Verified purchase

Tirzepatide
★★★★★

Shipped quickly from the Netherlands, and the COA confirmed the purity nicely. Third time ordering here without complaints.

Ruben T.

Verified purchase

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